Notes From the Clinic

Reflections, insights, and gentle guidance drawn from my work with women and children, shared to support you in your own healing journey.

PANS, Children's Health Ayelet Center PANS, Children's Health Ayelet Center

Could Folate Be the Missing Piece in PANS?

A 2024 study found folate receptor antibodies in 63.8% of children with PANS or PANDAS - meaning their brains may be unable to access folate even when blood levels look normal. This article explores what cerebral folate deficiency is, how it connects to symptoms like tics, OCD and anxiety, and what the current evidence says about folinic acid and leucovorin as interventions.

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